The Benefit of a Dietary Resveratrol Supplement, and Considerations for Formulating

The phrase “To your health” often accompanies a toast with red wine, highlighting its perceived health benefits. Red wine has long been investigated for its supposed disease-defying benefits, and product formulators have long sought to harness these benefits without the accompanying hangover.

Enter resveratrol, a plant compound found in red wine that offers intriguing antioxidant properties that can be used in wellness products. This article explores what resveratrol is, its sources, and the challenges associated with formulating dietary resveratrol supplements.

What is Resveratrol? 

Resveratrol is a plant compound with antioxidant properties belonging to the polyphenol group known as stilbenoids. It naturally occurs in the skin and seeds of red grapes and is also found in other foods and drinks such as red wine, blueberries, and cranberries. 

While resveratrol is most commonly distributed as a topical treatment to regenerate skin cells,  dietary supplements offer a more concentrated dose. However, these supplements may not be absorbed as easily as naturally occurring resveratrol. 

Most research and testing on the health benefits of resveratrol have been conducted on animals, with limited studies on its nutritional benefits for humans. As demand for resveratrol grows, further research is needed to fully understand its potential benefits. 

What Are the Benefits of Taking a Dietary Resveratrol Supplement?

The presumed benefits of taking resveratrol, even in doses as small as one gram, include: 

These benefits are also reported by users of dietary resveratrol supplements. However, it’s important to note that dietary resveratrol supplements are unregulated, and their efficacy can vary.

What Is the Best Form of Resveratrol To Take?

For formulators looking to incorporate resveratrol into their products, dietary supplements offer a higher concentration of this compound compared to natural food sources. In addition, novel water-dispersible forms of resveratrol, such as IsoCaps RES100, make higher concentrations possible for functional beverages. 

Resveratrol exists in two isomeric forms - trans resveratrol and cis resveratrol. Trans resveratrol is more chemically stable, more naturally abundant, and more easily absorbed and utilized by the body than cis resveratrol. In addition, most of the metabolism and bioactivity research for resveratrol has examined trans resveratrol. Therefore, the majority of dietary resveratrol supplements on the market utilize trans resveratrol. 

Considerations for Formulating with Resveratrol

The market for resveratrol products is expected to grow significantly in the near future. In 2021, the market size was approximately $110 million and is projected to nearly double to $220 million by 2030. 

Spoke Sciences’ ISOCaps RES100 offers water-dispersible resveratrol that can easily be incorporated into the water phase of any formulation. Utilizing Spoke’s nanoemulsion technology, which delivers greater density per milliliter, wellness product formulators can achieve greater resveratrol density in their products and functional beverages. 

Is Resveratrol Water Soluble? 

Resveratrol is a lipophilic compound, so it has low water solubility, which makes it difficult to manipulate. Resveratrol has greater solubility when mixed with solvents like ethanol. 

Which is why ISOCaps RES100 are so revolutionary. Through an advanced nano-emulsion technology, we’ve designed a resveratrol formula that finally solves significant industry pain points: water-solubility, stability, taste problems and manufacturability.

Advancing the Future of Resveratrol

The growing demand for resveratrol, combined with the potential for deeper understanding of its benefits, positions resveratrol one of the most promising compounds in the wellness market today. 

Innovative solutions like ISOCaps RES 100 will help product manufacturers deliver wellness products that offer a greater concentration of resveratrol, especially in functional beverages and other water-based formulations, without sacrificing taste or causing a hangover.

Contact us to learn more. 

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